Medication-Assisted Treatment (MAT) for Addiction
How FDA-approved medications combined with behavioral therapy improve outcomes for opioid and alcohol use disorder at Keystone Health Group.
Medication-assisted treatment (MAT) is the use of FDA-approved medications in combination with behavioral therapy and counseling to treat substance use disorders. MAT is the evidence-based standard of care for opioid use disorder and is also used for alcohol use disorder. Despite strong evidence of effectiveness, MAT remains underutilized due to stigma and misconceptions. At Keystone Health Group, our medical team provides MAT as part of a comprehensive, individualized treatment plan — not as a standalone intervention.
FDA-Approved Medications for Opioid Use Disorder
Three medications are FDA-approved for opioid use disorder: (1) Buprenorphine (Suboxone, Subutex, Zubsolv) — a partial opioid agonist that reduces cravings and withdrawal without producing significant euphoria; (2) Methadone — a full opioid agonist dispensed through licensed opioid treatment programs (OTPs) that eliminates withdrawal and cravings; (3) Naltrexone (Vivitrol) — an opioid antagonist that blocks the effects of opioids and reduces cravings. Our physicians determine which medication is most appropriate for each client.
FDA-Approved Medications for Alcohol Use Disorder
Three medications are FDA-approved for alcohol use disorder: (1) Naltrexone (oral or injectable Vivitrol) — reduces the rewarding effects of alcohol and cravings; (2) Acamprosate (Campral) — reduces the discomfort of post-acute withdrawal and supports abstinence; (3) Disulfiram (Antabuse) — causes an unpleasant reaction if alcohol is consumed, serving as a deterrent.
MAT Is Not 'Trading One Addiction for Another'
A common misconception about MAT — particularly buprenorphine and methadone — is that it is simply 'trading one addiction for another.' This is not accurate. MAT medications, when used as prescribed, restore normal brain function, reduce cravings, prevent withdrawal, and allow people to engage in behavioral therapy and rebuild their lives. The evidence is clear: MAT significantly reduces opioid use, overdose deaths, criminal activity, and HIV transmission.
Signs & Symptoms of Addiction
Our Treatment Approach
Frequently Asked Questions
How long do I need to take MAT medications?
The optimal duration of MAT varies by individual. Research suggests that longer duration of MAT produces better outcomes. The decision to taper off MAT should be made collaboratively with your physician based on stability, risk factors, and personal goals.
Does insurance cover MAT?
Yes. Most major insurance plans cover MAT medications under the Mental Health Parity and Addiction Equity Act. Our admissions team verifies your coverage for free.
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