Fentanyl Addiction Treatment in Los Angeles, California
Specialized treatment for fentanyl use disorder at Keystone Health Group — one of the most potent and dangerous opioids driving the overdose crisis.
Fentanyl is a synthetic opioid 50–100 times more potent than morphine and 50 times more potent than heroin. Originally developed for cancer pain management, illicitly manufactured fentanyl has become the primary driver of the opioid overdose crisis in the United States — responsible for the majority of overdose deaths. At Keystone Health Group, our clinical team provides specialized, evidence-based treatment for fentanyl use disorder, with protocols designed for fentanyl's unique pharmacological profile.
The Fentanyl Crisis
Illicitly manufactured fentanyl (IMF) has transformed the drug supply. Fentanyl is now found in counterfeit pills, heroin, cocaine, methamphetamine, and other substances — often without the user's knowledge. A lethal dose of fentanyl is approximately 2 milligrams — an amount invisible to the naked eye. This contamination of the drug supply means that anyone using illicit substances is at risk of fentanyl exposure.
Fentanyl Dependence and Withdrawal
Fentanyl's high potency means that physical dependence can develop rapidly. Fentanyl withdrawal follows the opioid withdrawal pattern but may be more intense due to the drug's potency. Fentanyl also accumulates in body tissues, which can complicate the withdrawal timeline. Our medical team is experienced in managing fentanyl-specific withdrawal challenges, including the timing of buprenorphine induction.
Medication-Assisted Treatment for Fentanyl
Medication-assisted treatment (MAT) with buprenorphine (Suboxone, Zubsolv) is the evidence-based standard for fentanyl use disorder. However, fentanyl's long tissue half-life requires careful timing of buprenorphine induction to avoid precipitated withdrawal. Our physicians are experienced in managing this challenge, using extended low-dose induction protocols when necessary.
Naloxone and Overdose Prevention
Naloxone (Narcan) is a life-saving opioid antagonist that reverses fentanyl overdose. Because fentanyl is so potent, multiple doses of naloxone may be required to reverse a fentanyl overdose. Our team educates all clients and their families on naloxone use and provides prescriptions for take-home naloxone as part of our harm reduction approach.
Signs & Symptoms of Addiction
Our Treatment Approach
Frequently Asked Questions
Why is fentanyl so much more dangerous than other opioids?
Fentanyl is 50–100 times more potent than morphine. A lethal dose is approximately 2 milligrams — an amount invisible to the naked eye. Its widespread contamination of the illicit drug supply means users may unknowingly consume fentanyl in substances they believe are something else.
Can Suboxone treat fentanyl addiction?
Yes, but fentanyl's long tissue half-life requires careful timing of buprenorphine induction. Starting buprenorphine too early after fentanyl use can precipitate severe withdrawal. Our physicians use extended low-dose induction protocols to manage this safely.
Does insurance cover fentanyl addiction treatment?
Yes. Most major insurance plans cover opioid use disorder treatment under behavioral health benefits. Our admissions team verifies your coverage for free.
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