Vicodin & Percocet Detox in Los Angeles, California
Medically supervised detox for hydrocodone (Vicodin, Norco) and oxycodone/acetaminophen (Percocet) dependency at Keystone Health Group.
Vicodin (hydrocodone/acetaminophen) and Percocet (oxycodone/acetaminophen) are among the most commonly prescribed — and most commonly misused — opioid pain medications in the United States. Both are combination products pairing an opioid with acetaminophen (Tylenol), and both carry significant potential for physical dependence and addiction with regular use. At Keystone Health Group, our medical team provides compassionate, evidence-based detox for Vicodin and Percocet dependency.
Vicodin (Hydrocodone) Dependence
Vicodin contains hydrocodone, a semi-synthetic opioid, combined with acetaminophen. It is prescribed for moderate to severe pain. With regular use, physical dependence can develop — meaning the body requires the drug to function normally and produces withdrawal symptoms when it is reduced or stopped. Vicodin withdrawal follows the typical opioid withdrawal timeline: onset within 8–24 hours of the last dose, peak at 36–72 hours, and resolution within 5–7 days.
Percocet (Oxycodone) Dependence
Percocet contains oxycodone, a slightly more potent opioid than hydrocodone, combined with acetaminophen. It is prescribed for moderate to severe pain. Percocet withdrawal is similar to Vicodin withdrawal in its timeline and symptom profile. Extended-release oxycodone formulations (OxyContin) have a longer duration of action and may produce a slightly different withdrawal course.
The Acetaminophen Consideration
Both Vicodin and Percocet contain acetaminophen, which can cause liver damage in high doses. People who have been misusing these medications in large quantities may have elevated liver enzymes or other signs of acetaminophen-related liver stress. Our medical team screens for this during the initial assessment and monitors liver function as part of the detox process.
Medication-Assisted Treatment
Our physicians use buprenorphine (Suboxone, Zubsolv) and/or the NSS-2 Bridge device to manage Vicodin and Percocet withdrawal. Buprenorphine significantly reduces withdrawal severity and cravings. Clonidine may be used to manage autonomic symptoms. All medications are physician-directed and monitored by our nursing staff.
Common Withdrawal Symptoms
How We Treat It
Frequently Asked Questions
How long does Vicodin or Percocet withdrawal last?
Withdrawal from Vicodin (hydrocodone) or Percocet (oxycodone) typically begins 8–24 hours after the last dose, peaks at 36–72 hours, and resolves within 5–7 days. Post-acute withdrawal symptoms (anxiety, sleep disturbance, mood changes) can persist for weeks.
Can I become addicted to Vicodin or Percocet if I take them as prescribed?
Physical dependence can develop with regular use even when taken as prescribed. This is a physiological adaptation, not a moral failing. If you have developed physical dependence, medical detox provides a safe and compassionate path to discontinuing the medication.
Is there a risk from the acetaminophen in Vicodin and Percocet?
Yes. High doses of acetaminophen can cause liver damage. People who have been misusing Vicodin or Percocet in large quantities should have their liver function assessed. Our medical team screens for this during the initial evaluation.
Does insurance cover Vicodin or Percocet detox?
Yes. Most major insurance plans cover medically necessary opioid detox under behavioral health benefits. Our admissions team verifies your coverage for free before admission.
Ready to Start Detox?
Same-day admissions available. Our team is here 24/7.
Call 855-83-RENEW Verify InsuranceSafe, supervised detox is one call away.
Same-day admissions available. Most insurance accepted.